|
Anaphylatoxin C5a
|
|
ILX:0100600
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anaphylatoxin receptor
|
|
ILX:0100601
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anaphylatoxin receptor - unspecified 1
|
|
ILX:0100602
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anaphylatoxin receptor - unspecified 2
|
|
ILX:0100603
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anaphylatoxin receptor - unspecified 3
|
|
ILX:0100604
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anaplastic
|
A morphology quality inhering in a neoplastic cell by virtue of the bearer's exhibiting breakdown of cell-cell interaction maintaining tissue architecture, proliferative dysregulation and bizarre modification to nucleus size and shape.
|
ILX:0100605
|
5
|
scicrunch
|
08/24/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
troy sincomb |
|
Anaspidea
|
|
ILX:0100606
|
5
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anastrozole
|
Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women. It is used both in adjuvant therapy (i.e. following surgery) and in metastatic breast cancer. It decreases the amount of estrogens that the body makes. Anastrozole belongs in the class of drugs known as aromatase inhibitors. It inhibits the enzyme aromatase, which is responsible for converting androgens (produced by women in the adrenal glands) to estrogens. Pharmacology: Anastrozole is a potent and selective non-steroidal aromatase inhibitor indicated for the treatment of advanced breast cancer in post-menopausal women with disease progression following tamoxifen therapy. Many breast cancers have estrogen receptors and growth of these tumors can be stimulated by estrogens. In post-menopausal women, the principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues, such as adipose tissue, with further conversion of estrone to estradiol. Many breast cancers also contain aromatase; the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. Anastrozole is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone. Mechanism of action: Anastrozole selectively inhibits aromatase. The principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues. Therefore, aromatase inhibition leads to a decrease in circulatin estrogen, leading to a decreased tumor mass or delayed progression of tumor growth in some women. Drug type: Approved. Investigational. Small Molecule. Drug category: Antineoplastic Agents. Antineoplastic Agents, Hormonal. Aromatase Inhibitors
|
ILX:0100607
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomic Region Modifier Sequence
|
Sequence of Items that modifies the anatomic region of interest in this Instance.
|
ILX:0100608
|
5
|
scicrunch
|
08/28/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
troy sincomb |
|
Anatomic Region Sequence
|
Identifies the general anatomic region imaged by the Protocol.
|
ILX:0100609
|
6
|
scicrunch
|
08/28/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
troy sincomb |
|
Anatomic Structure Space or Region Sequence
|
Anatomic structure, space or region that has been exposed to ionizing radiation. The sequence may have zero or one Items.
|
ILX:0100610
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomical cavity
|
Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure or two or more adjacent anatomical structures. Examples: pharyngeal recess space, nasal cavity, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. (FMA)
|
ILX:0100611
|
14
|
scicrunch
|
06/23/2020
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomical entity
|
Organismal continuant entity which is enclosed by the bona fide boundary of an organism or is an attribute of its structural organization. Examples: cell, heart, head, peritoneal cavity, apex of lung, anatomical term, sagittal plane (FMA).
|
ILX:0100612
|
13
|
scicrunch
|
06/23/2020
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomical Location
|
Spatial association relationship which describes the containment, adjacency, and anatomical coordinates of physical anatomical entities. Examples: anatomical containment, anatomical adjacency, anatomical coordinate (FMA).
|
ILX:0100613
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomical pathology
|
Branch of pathology.
|
ILX:0100614
|
3
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomical Pattern
|
|
ILX:0100615
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anatomy
|
The form and function of the structures of living organisms.
|
ILX:0100616
|
4
|
scicrunch
|
06/11/2021
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anchor Point
|
Location of a point in the image or Specified Displayed Area to which the Unformatted Text Value (0070,0006) is related, in Anchor Point Annotation Units (0070,0004), given as columnrow. Column is the horizontal offset and row is the vertical offset.
|
ILX:0100617
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anchor Point Annotation Units
|
Units of measure for the axes of the text anchor point annotation.
|
ILX:0100618
|
4
|
scicrunch
|
06/18/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
NeuroLex |
|
Anchor Point Visibility
|
Flag to indicate whether or not a visible indication (such as a line or arrow) of the relationship between the text and the anchor point is to be displayed.
|
ILX:0100619
|
5
|
scicrunch
|
08/28/2018
|
scicrunch |
term |
12/08/2016 |
0 |
NeuroLex |
troy sincomb |