X
X
Total 393357 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Extracellular matrix | A system of insoluble protein fibrils and soluble complexes composed of carbohydrate polymers linked to protein molecules, i.e. proteoglycans, in the extracellular space. Insoluble protein fibrils are mainly of two types: collagen and elastin; the soluble polymers consist of long carbohydrate chains, linked to proteins. | ILX:0104048 | 5 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extracellular Matrix Protein | Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., collagen, elastin, fibronectins, and laminin). (MSH) | ILX:0104049 | 4 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extracellular Space | That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid (Gene Ontology). | ILX:0104050 | 4 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extracellular Structure | Structure that exists outside the cell. | ILX:0104051 | 9 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extracellular Surface | ILX:0104052 | 4 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Extraction | A material separation in which a desired component of an input material is separated from the remainder. | ILX:0104053 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extradimensional shift task | A task in which multiple (typically two) stimuli are presented simultaneously and the subject must select the stimulus that matches the currently relevant rule. The relevant rule alternates or shifts" among multiple (typically two) rules. The rule represents the relevant task "dimension". The stimulus-response mappings are unique and constant within each possible rule dimension." | ILX:0104054 | 5 | scicrunch | 09/07/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Extrafusal fiber | Main contractile element of a muscle. | ILX:0104055 | 5 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extraocular muscle | One of a set of striated muscles that moves the eye | ILX:0104056 | 8 | scicrunch | 06/23/2020 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extrastriate cortex | A group of cortical areas related by direct or indirect connectivity to the striate area 17 and functionally involved primarily in vision. They include the parastriate area 18, the peristriate area 19 and adjacent areas in the parietal lobe and temporal lobe (Adapted from BrainInfo and Zilles-1990). | ILX:0104057 | 6 | scicrunch | 06/23/2020 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extreme capsule | Thin band of fibers separating the claustrum from the insular cortex | ILX:0104058 | 11 | scicrunch | 06/23/2020 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extrinsic neuron | An interneuron that extends projections between different neuropil domains. | ILX:0104059 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extrinsic no neuron | Any extrinsic neuron (FBbt_00003660) that has synaptic terminals in some nodulus (FBbt_00003680). | ILX:0104060 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Extrinsic pb neuron | Any extrinsic neuron (FBbt_00003660) that has synaptic terminals in some protocerebral bridge (FBbt_00003668). | ILX:0104061 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Eye | An organ that detects light. | ILX:0104062 | 11 | scicrunch | 06/12/2021 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Eye disease | * Diseases or defects of the eye. Use VISION DISORDERS for other pathology involving visual neural pathways. (PSY) * impairment of health or a condition of abnormal functioning of the organ of sight. (CSP) | ILX:0104063 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Eye movement | ILX:0104064 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Eye Saccade paradigm | A behavioral paradigm in which a subject makes a rapid eye movement relative to an initial target (JB). | ILX:0104065 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Ezetimibe | Ezetimibe is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Specifically, it appears to bind to a critical mediator of cholesterol absorption, the Niemann-Pick C1-Like 1 (NPC1L1) protein on the gastrointestinal tract epithelial cells as well as in hepatocytes. Pharmacology: Ezetimibe is in a class of lipid-lowering compounds that selectively inhibits the intestinal absorption of cholesterol and related phytosterols. Ezetimibe, administered alone is indicated as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia. It is also used in combination therapy with HMG-CoA reductase inhibitors. Ezetimibe has a mechanism of action that differs from those of other classes of cholesterol-reducing compounds (HMG-CoA reductase inhibitors, bile acid sequestrants, fibric acid derivatives, and plant stanols). Ezetimibe does not inhibit cholesterol synthesis in the liver, or increase bile acid excretion but instead localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. This causes a reduction of hepatic cholesterol stores and an increase in clearance of cholesterol from the blood; this distinct mechanism is complementary to that of HMG-CoA reductase inhibitors. Mechanism of action: Ezetimibe localizes and appears to act at the brush border of the small intestine and inhibits the absorption of cholesterol, leading to a decrease in the delivery of intestinal cholesterol to the liver. Drug type: Approved. Small Molecule. Drug category: Anticholesteremic Agents. Cholesterol Absorption Inhibitors | ILX:0104066 | 3 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| F bouton | Synaptic bouton found in the ventral horn of the spinal cord that range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles in electron microscopic preparations. | ILX:0104067 | 5 | scicrunch | 06/18/2018 | scicrunch | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
About
Base community for the SciCrunch.org infrastructure
Contact Us
X