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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Electrotonic conduction The passive spread of voltage changes between different regions of the neuronal membrane. ILX:0103724 5 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Electrotonic potential a passive or analog electrical potential, that decays in space and time according to the time and space constants. ILX:0103725 5 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Electrotonic Synapse Electrotonic synapses are gap junctions that allow the passage of ions directly from cell to cell. Ultrastructurally, it can be recognized as a 7 layered structure with 4 dense lines, two from each of the plasma membranes, alternating with 3 lighter lines. Electrotonic synapses are generally symmetric and display little or no dense material associated with the cytoplasmic face of the plasma membrane (Peters, Palay and Webster, 1991). ILX:0103726 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Electrotonus Passive spread of charge within a neuron. ILX:0103727 5 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Eletriptan Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches. (Wikipedia) Pharmacology: Eletriptan is a selective 5-hydroxytryptamine 1B/1D receptor agonist. In the anesthetized dog, eletriptan has been shown to reduce carotid arterial blood flow, with only a small increase in arterial blood pressure at high doses. While the effect on blood flow was selective for the carotid arterial bed, decreases in coronary artery diameter were observed. Eletriptan has also been shown to inhibit trigeminal nerve activity in the rat. Mechanism of action: Eletriptan binds with high affinity to 5-HT1B, 5-HT1D and 5-HT1F receptors, has modest affinity for 5-HT1A, 5-HT1E, 5-HT2B and 5-HT7 receptors, and little or no affinity for 5-HT2A, 5-HT2C, 5-HT3, 5-HT4, 5-HT5A and 5-HT6 receptors. Eletriptan has no significant affinity or pharmacological activity at adrenergic alpha1, alpha2, or beta; dopaminergic D1 or D2; muscarinic; or opioid receptors. Two theories have been proposed to explain the efficacy of 5-HT receptor agonists in migraine. One theory suggests that activation of 5-HT1 receptors located on intracranial blood vessels, including those on the arteriovenous anastomoses, leads to vasoconstriction, which is correlated with the relief of migraine headache. The other hypothesis suggests that activation of 5-HT1 receptors on sensory nerve endings in the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release. Drug type: Approved. Investigational. Small Molecule. Drug category: Anti-inflammatory Agents. Anti-migraine Agents. Selective Serotonin Agonists. Serotonin Agonists. Vasoconstrictor Agents ILX:0103728 2 scicrunch 01/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Elevated plus maze test A behavioral paradigm that serves as arodent model of anxiety and is also used as a screening test for putative anxiolytic or anxiogenic compounds and as a general research tool in neurobiological anxiety research. The test setting consists of a plus-shaped apparatus with two open and two enclosed arms, each with an open roof, elevated 40–70 cm from the floor. The model is based on rodents' aversion of open spaces. This aversion leads to the behavior termed thigmotaxis, which involves avoidance of open areas by confining movements to enclosed spaces or to the edges of a bounded space. In EPM this translates into a restriction of movement to the enclosed arms.Anxiety reduction in the plus-maze is indicated by an increase in the proportion of time spent in the open arms (time in open arms/total time in open or closed arms), and an increase in the proportion of entries into the open arms (entries into open arms/total entries into open or closed arms). Total number of arm entries and number of closed-arm entries are usually employed as measures of general activity. (adapted from Wikipedia: http://en.wikipedia.org/wiki/Elevated_plus_maze) ILX:0103729 4 scicrunch 08/24/2018 scicrunch term 12/08/2016 0 NeuroLex troy sincomb
Elevation The vertical distance of a point above or below a reference surface. ILX:0103730 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Eleventh thoracic dorsal root ganglion ILX:0103731 10 scicrunch 11/30/2020 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Eli Lilly and Company An American global pharmaceutical company with products sold in approximately 125 countries. Among other specialties, Lilly was the first company to mass-produce penicillin, the Salk polio vaccine, and insulin, including one of the first pharmaceutical companies to produce human insulin using recombinant DNA. Lilly is also the world's largest manufacturer and distributor of psychiatric medications. (Adapted from Wikipedia) ILX:0103733 4 scicrunch 08/24/2018 scicrunch term 12/08/2016 0 NeuroLex troy sincomb
Elliptic Oval which has two axes of symmetry, as produced by conical suction. ILX:0103734 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Elongated A quality inhering in a bearer by virtue of its length being notably higher than its width. ILX:0103735 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Elopocephala ILX:0103736 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embedded figures test In the embedded Figures Test, the research participant is shown a complex background figure and asked to describe it. After this, the participant is shown a target (such as the outline of a triangle) and asked to locate the target amid the background figure. ILX:0103737 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Emboliform nucleus the small wedge shaped nucleus interposed between the dentate and fastigial nuclei; it receives axons from Purkinje cells of the intermediate area of the cerebral hemispheres and most of its efferent connections travel via the superior cerebellar peduncle ILX:0103738 10 scicrunch 06/23/2020 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryo dog Between the first division of the zygote (a fertilized ovum) until it becomes a fetus, 24 to 30 days. ILX:0103739 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryo human Between the first division of the zygote (a fertilized ovum) until it becomes a fetus, 29 to 56 days. ILX:0103740 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryo mouse Between the first division of the zygote (a fertilized ovum) until it becomes a fetus, 8 to 13 days. ILX:0103741 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryo rat Between the first division of the zygote (a fertilized ovum) until it becomes a fetus, 11.5 to 16 days. ILX:0103742 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryo xenopus Between the first division of the zygote (a fertilized ovum) until it has reached a distinctively recognizable form, 12 to 36 hours. ILX:0103743 4 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex
Embryogenesis The development of an organism between fertilization and birth. ILX:0103744 3 scicrunch 06/18/2018 scicrunch term 12/08/2016 0 NeuroLex NeuroLex

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